| Blog.

MIT researchers have just developed CLAUDIA, a cutting-edge system that could change the game in chemotherapy treatment! Instead of relying on outdated dosing methods, CLAUDIA personalizes chemotherapy to each patient’s unique needs, improving safety and effectiveness. 🎯💉

Here’s how it works:

• Real-Time Monitoring: Every 5 minutes, CLAUDIA takes small blood samples and measures drug levels (specifically 5-fluorouracil) in the body.




• Instant Adjustments: If the drug levels aren’t in the “safe and effective” range, CLAUDIA automatically adjusts the infusion rate—either slowing it down or speeding it up.




• Personalised Dosing: Unlike traditional methods, which rely on formulas that don’t account for factors like body composition, genetics, or time-of-day metabolism, CLAUDIA adapts instantly to each patient’s needs.

Why is this better?

• Real-Time Adjustments: No more waiting weeks for lab results to adjust doses!




• Reduced Toxicity: Keeps drug levels safe, minimizing harmful side effects.




• Improved Effectiveness: Ensures patients get the right amount of drug to fight the tumour.

In animal tests, CLAUDIA kept drug levels in the target range 45% of the time, compared to just 13% with traditional methods—a huge improvement! 🐭

What's next? The researchers are aiming to fully automate CLAUDIA, making personalized chemotherapy even more accessible for various treatments.